Health Condition 1: T148- Other injury of unspecified body region
Conditions
Interventions
Intervention1: Tranexamic Acid spray: Tranexamic Acid before bleeding as compared to placebo spray
Control Intervention1: Tranexamic Acid (10% w/v): 10% w/v Tranexamic acid spray takes less time than
Sponsors
Shilpa Medicare Ltd.
Eligibility
Inclusion criteria
Inclusion criteria: Adult more than 18 years acute trauma patients with isolated extremity wounds with active bleeding Time since injury - less than 6 hours.
Exclusion criteria
Exclusion criteria: Paediatric trauma patient age less than 18 yrs Patients with known Blood Coagulopathy Patients on anti-platelet and anti-fibrinolytics Patients suffering with Co-morbidities and pregnant women Patients with a history of hypersensitivity to tranexamic acid and any of the ingredients
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate the efficacy of Tranexamic acid (TXA) spray 10% w/v with placebo (Placebo spray) on acute injury patients admitted to the ED.Timepoint: Proportion achieving haemostasis within 5, 10, 15 minutes compared to placebo | — |
Secondary
| Measure | Time frame |
|---|---|
| To evaluate the safety of the Tranexamic acid (TXA)spray 10% w/v with placebo (Placebo spray) on acute injury patients admitted to the ED.Timepoint: 1h, 12 h, & 24h post-spray application | — |
Countries
India
Contacts
Public ContactDr Tej Prakash Sinha
AIIMS
Outcome results
None listed