Health Condition 1: G810- Flaccid hemiplegia
Conditions
Interventions
Intervention1: Aspirin 75mg: Aspirin will be initiated after randomization after 24 hours after ICH onset up to 3 months, provided ICH growth has stopped by 24 hours after onset, followed by the Aspir
Sponsors
Indian Council of Medical Research, New Delhi
Eligibility
Inclusion criteria
Inclusion criteria: 1. first-ever ICH patients age more than 18 years presenting more than 24 hrs of the onset of stroke symptoms confirmed by brain imaging 2. alive more than 24 hours after non-traumatic ICH 3. not taking antiplatelet therapy or therapeutic dose anticoagulant therapy when randomised. 4. Consent obtained from the patient or legally accepted representative
Exclusion criteria
Exclusion criteria: 1. ICH is known to be due to trauma, a structural cause, for example, aneurysm, arteriovenous malformation, cerebral cavernous malformation, venous thrombosis, tumor, or hemorrhagic transformation of cerebral infarction 2. Volume of hematoma more than 60 ml 3. Glasgow comma scale less than equal to 5 4. they are pregnant, breastfeeding, or of childbearing potential and not using contraception 5. They are enrolled in a study that precludes co-enrolment 6. Sick or compromised patients 7. Geographical or other factors that prohibit follow-up
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome is to assess the efficacy of composite of all MACE: stroke, myocardial infarction, or death from any vascular cause (also including sudden death, pulmonary embolism, haemorrhage, and death from an unknown cause) Timepoint: End of the trial | — |
Secondary
| Measure | Time frame |
|---|---|
| The secondary outcome (safety) is major bleeding (all major haemorrhagic events that are fatal or result in hospitalisation), medication adherence and mRS (modified Rankin Scale)Timepoint: End of the trial | — |
Countries
India
Contacts
Public ContactDr Jeyaraj D Pandian
Christian Medical College and Hospital, Ludhiana
Outcome results
None listed