Health Condition 1: J449- Chronic obstructive pulmonary disease, unspecified Health Condition 2: T808- Other complications following infusion, transfusion and therapeutic injection Health Condition 3: G978- Other intraoperative and postprocedural complications and disorders of nervous system Health Condition 4: I978- Other intraoperative and postprocedural complications and disorders of the circulatory system, not elsewhere classified
Conditions
Interventions
Intervention1: Dexmedetomidine infusion: Dexmedetomidine, intravenous infusion dosage: 0.3 to 0.7mcg kg hr, Duration: 3 days
Control Intervention1: Combination of fentanyl and Midazolam Infusion: fen
Sponsors
NIL
Sri Narayani Hospital and Research Centre
Eligibility
Inclusion criteria
Inclusion criteria: Patients aged from 20 to 65 years. Patients who require mechanical ventilatory support Patients who require sedation & analgesic therapy Post operative surgical patients
Exclusion criteria
Exclusion criteria: Patients age more than 80 years Pregnancy lactation Patients with liver dysfunctions Patients with second- and third-degree heart block
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The study expected outcome will be dexmedetomidine infusion in mechanically ventilated patients, reducing incidence of adverse effects & delirium compared to other Groups.Timepoint: 3 years | — |
Secondary
| Measure | Time frame |
|---|---|
| intermittent interruption of sedative infusions helps to periodically evaluate the neurological status and level of sedation in critically ill patients. hence extubation can be planned earlier, which reduced duration of Mechanical ventilation in hours and number of days stay in intensive care units.Timepoint: 1 to 2 years | — |
Countries
India
Contacts
Public ContactVignesh J co investigator
Sri Narayani Hospital And Research Centre
Outcome results
None listed