Health Condition 1: -
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: )subjected to invasive mechanical ventilation for at least 24 hours. 2)suitable for spontaneous breathing trial(SBT) according to ICU protocol by the ICU doctor s team .
Exclusion criteria
Exclusion criteria: ) age more than 80 years old 2) primary diaphragmatic disease or trauma 3 undergone oesophageal and thoracic surgeries 4) pregnant women 5) electrolyte derangements and other correctable disorders 6)unstable haemodynamics
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary outcome is successful weaning defined as no ventilator support for 48 hours post-extubation. Secondary outcomes include diaphragmatic ultrasound parameters (excursion and thickening fraction measured pre-extubation and immediately post-extubation), total ventilation duration, ICU stay, re-intubation incidence, and mortality as recorded.Timepoint: no ventilator support for 48 hours post-extubation followed up | — |
Secondary
| Measure | Time frame |
|---|---|
| The secondary outcomes of the study explored the association between diaphragmatic weaning parameters & the Rapid Shallow Breathing Index (RSBI). A significant correlation was found between diaphragmatic excursion & RSBI, while no significant correlation was observed between diaphragmatic thickness fraction or the time to peak inspiratory amplitude of the diaphragm & RSBI.Timepoint: weaning success at 48 hours post extubation | — |
Countries
India
Contacts
Goa medical college