Exploring the Therapeutic Effect of Sandhaniya Mahakashaya: An ancient Ayurvedic approach to Knee pain management and Joint Health

Translational Research on Sandhaniya Mahakashaya Vis-a-Vis Janu Sandhigata Vata Knee Osteoarthritis - NIL

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/06/088174

Enrollment

Registered

2025-06-03

Start date

Unknown

Completion date

Unknown

Last updated

2025-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M170- Bilateral primary osteoarthritis of knee

Interventions

None listed

Eligibility

Inclusion criteria

Inclusion criteria: 1.The subjects coming under Diagnostic criteria will be selected for the study: Subjective Parameters: A) Subjects with following symptoms of Janu sandhigata vata will be taken for the study: a)Shula (Pain) b)Shotha (Swelling) c)Atopa (Crepitus) d)Vatapurna dhruti Sparsha (Joints feels like an inflated leather bag) e)Prasarana akunchanayo Vedana (Painful ROM) B) As per American college of Rheumatology (ACR) Clinical Classification criteria for the Knee OA, Using History and physical examination: a)Pain in the knee and 3 of the following, b)Over 50 years of Age c)Less than 30 minutes of morning stiffness d)Crepitus on active motion e)Bony Tenderness f)Bony enlargement g)No palpable warmth of synovium Objective Parameters: a)X-Ray: Knee joint Antero-Posterior and Lateral view: with Kellgren-Lawrence (KL)grading approach 2.The subjects of either gender over the age of 45-65 years. 3.Subjects diagnosed as Primary Knee Osteoarthritis. 4.Subjects fit for Matra basti will be selected for the study.

Exclusion criteria

Exclusion criteria: 1.Subjects with Secondary Knee Osteoarthritis. 2.Subjects diagnosed with other systemic disorders which may interfere with the course of the disease and its management. 3.Subjects who are incapacitate, bedridden and confined to wheel chair. 4.Pregnant women and Lactating mother.

Design outcomes

Primary

Measure	Time frame
The Sandhaniya Mahakashaya drugs is anticipated to support Sandhana (union) of joint structures, promoting healing and restoring joint function.Timepoint: At Baseline, On 9th day(For Matra Basti), On 11th day (For Shamananga Snehapana)	—

Secondary

Measure	Time frame
Overall Improvement in the Quality of LifeTimepoint: on 21st day	—

Countries

India

Contacts

Public ContactDr Mallika

Government Ayurveda Medical College and Hospital, Mysuru

dr.shreevathsa@rediffmail.com9449772701

Outcome results