Comparison of perineural versus intravenous dexamethasone as an adjuvant to 0.5 percent bupivacaine for upper limb surgeries.

Comparison of perineural versus intravenous dexamethasone as an adjuvant to 0.5 percent Bupivacaine in ultrasound guided infraclavicular brachial plexus block for upper limb orthopaedic surgeries. A Randomised, double blind study. - Nil

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/06/088130

Enrollment

Registered

2025-06-03

Start date

Unknown

Completion date

Unknown

Last updated

2025-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: 0.5% bupivacaine 25ml+ 4mg of dexamethasone stat dose: Single dose of 0.5% bupivacaine 25ml+ 4mg of dexamethasone given perineurally Control Intervention1: 0.5% bupivacaine 25ml+ 4mg of

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients willing to give written informed consent 2. ASA I and II 3. BMI greater or equal to 25

Exclusion criteria

Exclusion criteria: 1. Patient refusal of regional anaesthesia 2. Patients with coagulopathy, INR greater or equal to 1.5 3. Infection at site of block 4. Patients with peripheral neuropathy 5. Allergy to study drug 6. H/O active seizure disorder or active neurological disorder

Design outcomes

Primary

Measure	Time frame
To compare perineural vs intravenous dexamethasone as an adjuvant to 0.5% bupivacaine in terms of duration and onset time of sensory and motor blockadeTimepoint: 0 min, 30 min, 1 hr, 2hr, 4hr, 8hr, 12hr, 16hr, 20hr, 24hr	—

Secondary

Measure	Time frame
Time to first rescue analgesia and Intraoperative and postoperative hemodynamic stabilityTimepoint: 0 min, 30 min, 1 hr, 2hr, 4hr, 8hr, 12hr, 16hr, 20hr, 24hr	—

Countries

India

Contacts

Public ContactDr Ramesh Kumar P B

BGS Global Institute of Medical Sciences

shilpahl@yahoo.com9916950558

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026