Health Condition 1: L00-L99- Diseases of the skin and subcutaneous tissue
Conditions
Interventions
Intervention1: Autologous platelet rich plasma therapy: We will take whole blood of 10-40ml according to wound size and platelet rich plasma will be separated and used over diabetic foot ulcers.APRP
Sponsors
Department of general surgery Aiims Deoghar
Eligibility
Inclusion criteria
Inclusion criteria: Age from 18 -80.Both gender.Non healing ulcer (diabetic) more than 6 weeks.Ulcer of grade I and II (Wagner grade).Ulcer of size more than 1 cm and less than 10cm and depth less than 2 cm.Blood sugar range 150-200 gm/dl and HbA1C level 6.5 to 8 mg/dl g) Patient agrees to donate blood in order to prepare autologous platelet-rich plasma h) Consent to participate in study
Exclusion criteria
Exclusion criteria: Non diabetic non-healing ulcers (like pressure sores, Venous ulcer and malignant ulcers).Infected and gangrenous DFUs( Evidence of osteomyelitis in the affected foot & Exposed tendons, ligaments, or bones at the base of ulcer. Patient with Platelet dysfunction disorder ,CKD, thrombocytopenia, pregnant and lactating , taking NSAIDS and steroids. Patients who received radiotherapy or chemotherapy at the time of study or within 3 months of its beginning. Patients with hypersensitivity and/or allergy to any of the components of treatment product
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Reduction of wound sizeTimepoint: 12 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| Rate of wound healingTimepoint: 12 weeks | — |
Countries
India
Contacts
Public ContactDr Amardeep Kumar
Aiims Deoghar
Outcome results
None listed