Effectiveness of two different chemicals in managing extraction socket after tooth removal

Efficacy of aloe vera-bromelain and hyaluronic acid in the management of post extraction socket: a randomized controlled trial - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/06/088058

Enrollment

124

Registered

2025-06-02

Start date

Unknown

Completion date

Unknown

Last updated

2025-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K039- Disease of hard tissues of teeth,unspecified

Interventions

Intervention1: aloe vera and bromelain: 500mg of aloe vera extract and bromelain extract will be weighed using digital weighing machine which will then be mixed with 2ml of saline in a sterile dappen

Eligibility

Inclusion criteria

Inclusion criteria: Individuals who are willing to give their consent. Individuals with completely erupted firm posterior tooth that needs extraction due to dental caries or orthodontic treatment.

Exclusion criteria

Exclusion criteria: Uncooperative individuals or individuals who did not consent to participate in the study. Individuals with systemic diseases or disorders that could affect healing. Deleterious habits such as smoking and/or alcohol consumption. Lactating and pregnant women.

Design outcomes

Primary

Measure	Time frame
Effect on extraction socketTimepoint: 24 hours 72 hours 7 days 14 days	—

Secondary

Measure	Time frame
pain and healing of extraction socketTimepoint: 24hrs, 72 hrs, 7 days, 14 days	—

Countries

India

Contacts

Public ContactDr Shivlingesh KK

Institute of Dental Sciences, Bareilly

shivgesh@gmail.com9560277157

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026