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Study on how probiotic and different mouthwashes affect dental plaque, mouth acidity and bacteria levels in saliva

Evaluation of effectiveness of probiotics, chlorhexidine and fluoridecontaining mouthwash on Plaque Index, Salivary pH and Streptococcus mutans count - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/06/088015
Enrollment
64
Registered
2025-06-02
Start date
Unknown
Completion date
Unknown
Last updated
2025-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Probiotic - enKor-D: 1g (1 sachet) OD for 30 days Intervention2: Fluoride containing mouthwash- Listerine Total Care Mild Taste: 20ml mouth rinse for 30 seconds, BD for 1 month Interven

Sponsors

Nikita
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Subjects with good dental and general health, not using any antibiotics or mouthwashes 3-4 weeks before the start of the study, and maintaining regular oral hygiene.

Exclusion criteria

Exclusion criteria: Subjects with poor oral hygiene, maligned or overcrowded teeth, history of allergies, metabolic diseases such as diabetes or other medical conditions that could interfere with the study, drug addicts, pregnant or nursing women, and participation in any concurrent oral care study

Design outcomes

Primary

MeasureTime frame
To evaluate the use of different mouthwashes and probiotic on oral microflora causing caries and plaque deposition on tooth surface and change in acidity level in mouthTimepoint: At baseline ,15 days and 1 months

Secondary

MeasureTime frame
Assessment of different mouthwashes & probiotic on oral microflora & their colony formation with their pHTimepoint: At baseline, 15 days & 1 month

Countries

India

Contacts

Public ContactDr Sonali Taneja

ITS-CDSR

sonalitaneja@its.edu.in9891688100

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026