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A study on the effect of laser light therapy and steroid ointment in patients with white patches in the mouth that is oral lichen planus

Comparison of Laser Photobiomodulation and Topical 0.05 percentage Clobetasol Propionate in the treatment of Oral lichen planus :A Randomized Controlled Trial

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/06/088000
Enrollment
44
Registered
2025-06-02
Start date
Unknown
Completion date
Unknown
Last updated
2025-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Photobiomodulation Therapy: 4 J per point for 10 seconds a total of 8 sessions in a month Control Intervention1: Clobetasol Propionate 0.05 percentage: Topical Application TID for 4 we

Sponsors

KMCT Dental College
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Normal physical examination results before medication

Exclusion criteria

Exclusion criteria: Presence of severe systemic diseases or other severe oral mucous diseases or under cancer treatment Previous history of photobiomodulation therapy History of anti-inflammatory drugs treatment within a month Presence of lichenoid reaction caused by amalgam fillings or drugs known to cause drug induced lichenoid reaction Pregnancy intention of pregnancy lactation or recent use of steroid hormone based contraceptives OLP patients with skin lesions History of psychiatric disorders Participation in any other clinical trials in the 3 months before enrollment in this study Those lesions with epithelial dysplasia in histopathological evaluation Patient who are allergic to the drugs used in the study

Design outcomes

Primary

MeasureTime frame
Reduction in pain severity measured using the Visual Analog Scale and reduction in lesion severity assessed using the REU score that is Reticulation Erythema UlcerationTimepoint: At baseline 2 weeks 4 weeks after 1 month

Secondary

MeasureTime frame
NILTimepoint: NIL

Countries

India

Contacts

Public ContactRanchini V

Kerala university of health sciences

ashirkr@kmctdentalcollege.org

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026