Measuring and comparing serum protein lumican levels in patients with healthy gum, chronic gum disease (periodontitis) with and without diabetes before and after scaling and root planing: A Randomized Controlled Trail

Estimation and comparison of serum lumican level in patients with healthy gingiva, chronic periodontitis with and without diabetes mellitus before and after non-surgical periodontal therapy: A randomized controlled clinical study - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/06/087996

Enrollment

Registered

2025-06-02

Start date

Unknown

Completion date

Unknown

Last updated

2025-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis Health Condition 2: E119- Type 2 diabetes mellitus without complications

Interventions

Intervention1: Test group (Group A) chronic periodontitis without diabetes: Scaling and root planing and evaluation of serum lumican level.: 2 ml of venous blood would be collected from all the subjec

Eligibility

Inclusion criteria

Inclusion criteria: Male and female systemically healthy patients. Male and female patients with chronic periodontitis, should be otherwise healthy. Male and female patients with chronic periodontitis and diabetes mellitus, should not have any other systemic disease. Presence of at least 30% sites with probing depth of 4 mm to 6mm

Exclusion criteria

Exclusion criteria: Pregnancy and lactation Any systemic condition other than diabetes mellitus Patient unwilling to participate in the study Smoking or alcohol habits Pharmacological therapies for periodontal disease for last six months

Design outcomes

Primary

Measure	Time frame
Reduction in serum lumican levelTimepoint: Baseline and 3 months	—

Secondary

Measure	Time frame
Reduction in probing depthTimepoint: Baseline and 3 months	—

Countries

India

Contacts

Public ContactDr James Samuel

Goa Dental College and Hospital, Goa

jamessamueldental@gmail.com9544871089

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026