Evaluating the effect of Gentle Electrical Pulse Therapy in improving Jaw muscle strength and function

Assessing the Impact Of Electrical Stimulation on Masticatory Muscles in Myofunctional Appliance Therapy: A Randomized Controlled Trial - NIL

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/05/087959

Enrollment

Registered

2025-05-30

Start date

Unknown

Completion date

Unknown

Last updated

2025-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M261- Anomalies of jaw-cranial base relationship

Interventions

Intervention1: Group 1- Twin Block patients with Neuromuscular Electrical Stimulation (NMES): Group 1 subjects will be provided with Neuromuscular Electrical Stimulation on the Masseter,Temporalis an

Eligibility

Inclusion criteria

Inclusion criteria: 1. Skeletal Class II division 1 malocclusion with retrognathic mandible 2. Increased overjet not less than 5mm 3. Mixed or permanent dentition 4. Positive pre-treatment Visualized Treatment Objective(VTO) 5. Minimum crowding in dental arch requiring no extraction of any permanent teeth 6. Patients giving consent for participating in the study

Exclusion criteria

Exclusion criteria: 1.History of previous orthodontic treatment 2.Class II division 2 malocclusion 3.Any systemic disease affecting bone and general growth 4.Presence of any craniofacial syndromes 5.Presence of Temporomandibular Joint disorders 6.Presence of neuromuscular disorders

Design outcomes

Primary

Measure	Time frame
1. Efficacy outcomes demonstrating NMES response rates, including stimulation-induced voluntary contractions of the masticatory muscles, leading to increased muscle strength and function. 2. Identification of physiological parameters that predict treatment response and provide insight into resistance mechanisms, potentially guiding future therapeutic strategies for optimizing NMES effectiveness in masticatory muscle rehabilitation.Timepoint: Pre treatment,1 month,3 months,6 months	—

Measure

Time frame

1. Efficacy outcomes demonstrating NMES response rates, including stimulation-induced voluntary contractions of the masticatory muscles, leading to increased muscle strength and function. 2. Identification of physiological parameters that predict treatment response and provide insight into resistance mechanisms, potentially guiding future therapeutic strategies for optimizing NMES effectiveness in masticatory muscle rehabilitation.Timepoint: Pre treatment,1 month,3 months,6 months

—

Secondary

Measure	Time frame
Evaluation of improvements in facial profile or functional jaw performance induced by NMES-based retraining of masticatory muscles.Timepoint: Pre treatment,1 month,3 months,6 months	—

Countries

India

Contacts

Public ContactDr Shifa Sulthana A J

All India Institute Of Medical Sciences Bathinda

rana.shailu0612@gmail.com8750146251

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026