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A Prospective double blind study in Pediatric post cardiac surgical patients with lobar atelectasis, to compare between nebulised Mesna and nebulised N Acetyl Cysteine as an adjunct to respiratory physiotherapy.

A Pragmatic Prospective double blind study comparing nebulised Mesna and nebulised N Acetyl Cyestine as an adjunct in respiratory physiotherapy for post operative pediatric cardiac surgical patients with lobar atelectasis A perioperative Pulmonary bundle. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/05/087942
Enrollment
100
Registered
2025-05-30
Start date
Unknown
Completion date
Unknown
Last updated
2025-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I998- Other disorder of circulatory system

Interventions

Intervention1: NIL: NIL Intervention2: NIL: NIL Control Intervention1: Nebulised Mesna: Post extubation, children with confirmed lung collapse by chest X Ray or USG will be nebulised with 10% solution

Sponsors

Dr Venuthurupalli SP Rajesh
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All post pediatric cardiac surgery patients who develop lung collapse post extubation and that is confirmed ny Chest XRay or USG.

Exclusion criteria

Exclusion criteria: Children who are on mechanical ventilator preoperatively, preoperative pneumonia, airway anamolies, children having plueral effusion, children having pneumothorax.

Design outcomes

Primary

MeasureTime frame
Time for recruitment of collapsed lung.Timepoint: Post extubation, 24 hour post extubation, 48 hour post extubation.

Secondary

MeasureTime frame
Nasal CpAP requirement.Timepoint: Post extubation, 24 hour post extubation, 48 hour post extubation.

Countries

India

Contacts

Public ContactVenuthurupalli S P Rajesh

UN Mehta Institute of Cardiology and Research Centre.

rajeshvsp.88@gmail.com7799026386

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026