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Comparison of dual versus triple drug regimen for spontaneous expulsion of mid and lower ureteric stones less than 10 mm

A Prospective Comparative Study on the Efficacy of Double Drug (tamsulosin and deflazacort) versus Triple Drug Regimens (tamsulosin, tadalafil, and deflazacort) in Medical Expulsion Therapy of Mid and Distal Ureteric Calculi in the Central Indian Population - MET

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/05/087935
Enrollment
60
Registered
2025-05-30
Start date
Unknown
Completion date
Unknown
Last updated
2025-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N201- Calculus of ureter

Interventions

Intervention1: FDA/DCGI APPROVED THREE DRUGS COMBINATION (TRIPLE DRUG REGIMEN ): Tamsulosin 0.4 mg once daily for 4 weeks Tadalafil 5 mg once daily for 4 weeks Deflazacort 30 mg once daily for 10 da

Sponsors

no sponsor
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Radiologically confirmed mid and distal ureteric calculus less than 10 mm

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Stone expulsion rate confirmed by NCCT KUBTimepoint: 28 days—

Secondary

MeasureTime frame
Time to stone expulsion (in days from the start of treatment)Timepoint: ;Number of colic episodesTimepoint: 4 weeks;Analgesic use (diclofenac in mg)Timepoint: 4 weeks;Adverse effects (dizziness, headache, hypotension, etc.) Timepoint:—

Countries

India

Contacts

Public ContactDR KAPIL RATHORE

AIIMS BHOPAL

rathorekapil07@gmail.com7014859456

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026