Health Condition 1: D249- Benign neoplasm of unspecified breast Health Condition 2: C509- Malignant neoplasm of breast of unspecified site
Conditions
Interventions
Intervention1: NIL: NIL
Control Intervention1: NIL: NIL
Sponsors
Maulana Azad Medical College
Eligibility
Inclusion criteria
Inclusion criteria: Newly diagnosed cases of benign and malignant breast lesions on FNAC/Tru-cut biopsy specimens.
Exclusion criteria
Exclusion criteria: Insufficient material on FNAC/Tru-cut biopsy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Percentage of circulating Myeloid derived suppressor cells(MDSCs) in benign, malignant breast lesions and controls.Timepoint: Baseline | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.Association of circulating PMN-MDSCs, Mo-MDSCs and e-MDSCs in benign and malignant breast lesions with clinicopathological parameters like age, parity, size of the lump, overlying skin changes, nipple discharge, cervical and axillary lymph nodes, organomegaly and pathological parameters like type of benign lesion, TNM staging, histopathological grading, hormone status, number of lymph nodes involved and metastasis. 2.Difference in percentages of circulating MDSCs in malignant breast lesions, prechemotherapy/ presurgery and post-chemotherapy/post-surgery.Timepoint: Baseline | — |
Countries
India
Contacts
Public ContactDr Prerna Arora
Maulana Azad Medical College
Outcome results
None listed