Comparison of injectable platelet rich fibrin and laser therapy in reducing side effects of maxillary assisted rapid palatal expansion.

Comparison of efficacy of injectable platelet rich fibrin and low level laser therapy in reducing buccal alveolar bone resorption following maxillary assisted rapid palatal expansion : A Randomised Controlled Trial - nil

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/05/087747

Enrollment

Registered

2025-05-28

Start date

Unknown

Completion date

Unknown

Last updated

2025-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K088- Other specified disorders of teethand supporting structures

Interventions

Intervention1: injectable platelet rich fibrin: 10 ml of blood sample will be collected from participants. The centrifugation protocol required one cycle only (700 rpm for 3min), and the yellow orang

Eligibility

Inclusion criteria

Inclusion criteria: Patient in late adolescent stage [Cervical vertebra maturation index (CVMI) 5,6] assessed by lateral cephalogram, Patient in age group of 16-25years, Unilateral or bilateral posterior crossbite, Maxillary transverse deficiency.

Exclusion criteria

Exclusion criteria: Patients with systemic problems and under medication, Poor oral hygiene patients with physical and psychological limitations, Craniofacial anomalies, Previous orthodontic treatment.

Design outcomes

Primary

Measure	Time frame
Buccal bone thickness and height of supporting teeth remained unaffected after MARPETimepoint: T0: Pre treatment T1: 6 months after MARPE	—

Secondary

Measure	Time frame
Both i-PRF and LLLT are equally effective in reducing alveolar bone resorption of the posterior teeth following MARPETimepoint: T0: Pre treatment T1: 6 months after MARPE	—

Countries

India

Contacts

Public ContactAnshika Gandhi

Maulana azad institute of dental sciences

anshikagandhi2412@gmail.com9818332449

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026