Observing the effect of epidural dexmedetomidine for intraoperative cardiac stability and better postoperative pain management in patients undergoing open abdominal surgeries under general anaesthesia

Effect of epidural dexmedetomidine as an adjuvant on intraoperative haemodynamics and postoperative analgesia in patients undergoing open abdominal surgeries under general anaesthesia - a one year single blinded randomized controlled trial - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/05/087743

Enrollment

Registered

2025-05-28

Start date

Unknown

Completion date

Unknown

Last updated

2025-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K639- Disease of intestine, unspecified Health Condition 2: K319- Disease of stomach and duodenum, unspecified Health Condition 3: K87- Disorders of gallbladder, biliarytract and pancreas in diseases classified elsewhere Health Condition 4: O- Medical and Surgical Health Condition 5: N998- Other intraoperative and postprocedural complications and disorders of genitourinary system

Interventions

Intervention1: DEXMEDETOMIDINE: Usage of Dexmedetomidine as an adjuvant to Ropivacaine in patients receiving epidural anaesthesia in one group, the other group shall not receive dexmedetomidine, (only

Eligibility

Inclusion criteria

Inclusion criteria: All patients aged 18-60 yrs, undergoing open abdominal surgeries under general+epidural anaesthesia, ASA Grades I and II patients, and patients whose height is between 155-165cms.

Exclusion criteria

Exclusion criteria: Patients contraindicated to epidural anaesthesia, patients with chronic cardiac or respiratory illness, sepsis, psychiatric illness, diabetic neuropathy.

Design outcomes

Primary

Measure	Time frame
effect of epidural dexmedetomidine on systolic blood pressure, diastolic blood pressure, mean arterial blood pressure and heart rateTimepoint: post induction of general+epidural anaesthesia	—

Secondary

Measure	Time frame
quality of postoperative analgesia using VAS score evaluationTimepoint: post-operative period	—

Countries

India

Contacts

Public ContactTanushree Potluri

Jawaharlal Nehru Medical College, KLE University

shreeyenni@yahoo.co.in9035073998

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026