Use of Platelet rich fibrin with and without Metronidazole to reduce infection

Comparative evaluation of wound healing in periapical lesion using platelet rich fibrin with and without incorporated metronidazole Randomized controlled trial - NIL

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/05/087735

Enrollment

Registered

2025-05-27

Start date

Unknown

Completion date

Unknown

Last updated

2025-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Metronidazole incorporated Platelet Rich Fibrin: 10 ml blood will be withdrawn and 10 ml Metronidazole will be added to the blood . Solution will be centrifuged at 3000 rpm for 15 minut

Eligibility

Inclusion criteria

Inclusion criteria: Teeth indicated for extraction having periapical lesions

Exclusion criteria

Exclusion criteria: Patients with co-morbidities which delay wound healing

Design outcomes

Primary

Measure	Time frame
Wound healingTimepoint: Wound healing - Week 1 and week 2	—

Secondary

Measure	Time frame
reduced infection rateTimepoint: week 1 and week 2	—

Countries

India

Contacts

Public ContactDr Kalyani Bhate

Dr DY Patil Dental College And Hospital Dr DY Patil Vidyapeeth Pimpri Pune

kalyani.bhate@dpu.edu.in9822099311

Outcome results