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A study to compare nerve block and lignocaine infusion on pain relief after breast cancer surgery

Efficacy of single shot pectoral plane (PEC I and PEC II) block versus perioperative lignocaine infusion for postoperative analgesia after radical mastectomy : a randomized controlled trial - NIL

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/05/087729
Enrollment
82
Registered
2025-05-27
Start date
Unknown
Completion date
Unknown
Last updated
2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C509- Malignant neoplasm of breast of unspecified site

Interventions

Intervention1: Group L- Intravenous Lignocaine infusion (test group): Patients in this group will receive a 1.5 mg/kg loading dose of 2% lidocaine solution via IV infusion, administered slowly over 3-

Sponsors

Post Graduate Institute Of Medical Education And Research,Chandigarh
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA I and II female patient undergoing unilateral mastectomy.

Exclusion criteria

Exclusion criteria: Patient refuses to participate, unable to understand the VAS score, with pre-existing infection at the site of block, with morbid obesity and sensitive to local anaesthetic

Design outcomes

Primary

MeasureTime frame
Area under the curve (AUC) of the visual analog score (VAS) sccore of pain vs time over 24hrTimepoint: At 0hr, 0.5hr, 1hr, 2hr, 4hr, 6hr, 8hr, 12hr and 24hr in postoperative period

Secondary

MeasureTime frame
Pain score (VAS)Timepoint: 0hr, 0.5hr, 1hr, 2hr, 4hr, 6hr, 8hr, 12hr, 24hr and 3 month after surgery;Postoperative nausea vomiting number of episodes, dose of antiemetics requiredTimepoint: post operative period;Time to 1st rescue analgesiaTimepoint: ;Cumulative dose of rescue analgesiaTimepoint: ;Quality of recovery score QoR-15Timepoint: ;Richmond agitation sedation score (RASS) for lignocaine infusionTimepoint: ;Complications for E.g. LA toxicity, vascular puncture, pleural puncture.Timepoint:

Countries

India

Contacts

Public ContactAshish Singh Aditya

Post Graduate Institute of Medical Education and Research

ashish09399@gmail.com9914406496

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026