Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Inj Lignocaine 0.5mg/kg: Study participants will receive e 0.5mg/kg of inj lignocaine diluted in 5ml normal saline 1 minute before induction of anaesthesia with inj propofol
Control Int
Sponsors
Regional Institute of Medical Sciences
Eligibility
Inclusion criteria
Inclusion criteria: Patients of age group 18 to 60 years. Patients of ASA-PS grade I or II.
Exclusion criteria
Exclusion criteria: Patients with history of allergy to propofol and the study drugs. Patients with anticipated difficult venous access. Patients with neurological deficits or psychiatric disorders. Patients with history of drug abuse (alcohol, sedative, and analgesic). Patients with cardiac disease (hemodynamically unstable, ischaemic heart disease), hepatic, renal, pulmonary disease and seizures Patients with morbid obesity. Patients with pregnancy and breastfeeding. Patients with acute or chronic pain syndromes. Patients with disorders of lipid metabolism. Patients having problems in communication. Patients requiring rapid sequence induction. Patients with thrombophlebitis.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intensity of pain during propofol injectionTimepoint: Intensity of pain during propofol injection, assessed using a verbal response scale within 30 seconds of propofol administration. | — |
Secondary
| Measure | Time frame |
|---|---|
| Heamodynamic changes (hypotension, bradycardia, hypertension, tachycardia) after propofol administration.Timepoint: Heamodynamic changes (hypotension, bradycardia, hypertension, tachycardia) baseline before, during and 1, 3 minutes after propofol administration. | — |
Countries
India
Contacts
Public ContactRupendra S Thokchom
Regional Institute of Medical Sciences
Outcome results
None listed