Evaluating Placental Extract and Oxygen-Enriched Gels as Add-On Treatments to Deep Cleaning in Moderate Gum Disease: A Randomized Clinical Trial

Evaluating the efficacy of placental extract gel (Placentrex) and high concentration oxygen gel (Blue M) as an adjunct to scaling and root planning in stage II periodontitis patients: A randomized controlled clinical trial - NIL

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/05/087694

Enrollment

Registered

2025-05-27

Start date

Unknown

Completion date

Unknown

Last updated

2025-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: Evaluating the efficacy of Placentrex gel and BlueM TM gel as an adjunct to scaling and root planing in the treatment of stage II periodontitis patients.: Patients with at least two

Eligibility

Inclusion criteria

Inclusion criteria: a. Patients within age group of 18 to 45 years. b. Stage II periodontitis patients with at least two non-adjacent teeth with probing depth 3 to 4 mm. c. Systemically healthy patients

Exclusion criteria

Exclusion criteria: a. Patients using protective or orthodontic appliances. b. Patients who are smokers or using any other tobacco products. c. Female patients who are pregnant and lactating.

Design outcomes

Primary

Measure	Time frame
Complete scaling and root planing will be done. Only those sites with probing pocket depth of 3-4mm will be selected. Each Patient will be randomly divided into three groups. Baseline clinical parameters (Clinical parameters like Gingival Index, Modified Papillary Bleeding Index, Probing Pocket Depth and Clinical Attachment Level) will be recorded. Administration of Placentrex gel and Blue M TM gel in the periodontal pockets up to the marginal gingiva will be carried out.Timepoint: Follow up after 4 weeks and 8 weeks will done to check the clinical parameters	—

Measure

Time frame

Complete scaling and root planing will be done. Only those sites with probing pocket depth of 3-4mm will be selected. Each Patient will be randomly divided into three groups. Baseline clinical parameters (Clinical parameters like Gingival Index, Modified Papillary Bleeding Index, Probing Pocket Depth and Clinical Attachment Level) will be recorded. Administration of Placentrex gel and Blue M TM gel in the periodontal pockets up to the marginal gingiva will be carried out.Timepoint: Follow up after 4 weeks and 8 weeks will done to check the clinical parameters

—

Secondary

Measure	Time frame
NilTimepoint: Nil	—

Countries

India

Contacts

Public ContactDarshana Borawake

Department of Periodontology, MGVs KBH Dental college and Hospital, Panchavati, Nashik

1999borawakedarshana@gmail.com08090020029

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026