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Comparing the effect of topical fluorides on salivary bacteria streptococcus mutans levels and salivary pH in children with early childhood caries

Comparing the effect of MI varnish, 38% silver diamine fluoride and nano silver fluoride on salivary streptococcus mutans levels and salivary pH in children with early childhood caries an invivo study - nil

Status
Active, not recruiting
Phases
Phase 2Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/05/087691
Enrollment
45
Registered
2025-05-27
Start date
Unknown
Completion date
Unknown
Last updated
2025-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K029- Dental caries, unspecified

Interventions

Intervention1: salivary streptococcus mutans and salivary pH levels: Intergroup evaluation and correlation of salivary streptococcus mutans and salivary pH levels before and after one month and three

Sponsors

Dr Ganavi G Nayak
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Children with 3 to 6 years of age of both genders 2.Children with DC greater than or equal to 3 in primary teeth, ICDAS II criteria , CODE 02 and 03 3. Parents giving consent for the study

Exclusion criteria

Exclusion criteria: 1. Children who received fluoride topical application during the last 1 month 2. Children requiring special health care needs. 3.Pulpally involved and grossly decayed teeth. 4.Children who were on antibiotic therapy within the past 3 months. 5.Children with genetic diseases or syndrome

Design outcomes

Primary

MeasureTime frame
Evaluate salivary streptococcus mutans levels and salivary pH before and after application of MI varnish,38% SDF and NSF in children with ECC using ELISATimepoint: Base line 1 month 3 month

Secondary

MeasureTime frame
Correlation and comparision of intragroup and intergroup salivary streptococcus mutans level and salivary pH levels before and after application of MI varnish,38% SDF and NSF in childrden with ECC using ELISATimepoint: Base line 1 month 3 month

Countries

India

Contacts

Public ContactDr Ganavi G Nayak

Rajarajeswari dental college and hospital bengaluru

jaya.vrushabh@gmail.com09880038038

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026