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Evaluating Fat-Dissolving Injections versus Surgery for Treating Lipomas: A Clinical Trial

Surgical excision vs intralesional phosphatidylcholine on management of lipoma - A randomized controlled trial.

Status
Active, not recruiting
Phases
Phase 2Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/05/087687
Enrollment
106
Registered
2025-05-27
Start date
Unknown
Completion date
Unknown
Last updated
2025-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Injection phosphatadiylcholine: 0.3 ml of the drug will be injected at equidistant area of one centimetric within the center of the lipoma Frequency: Every 2 weeks End point : 12 weeks

Sponsors

AIIMS Bhubaneswar
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Superficial Subcutaneous lipoma Size less than 5 cm in greatest dimension

Exclusion criteria

Exclusion criteria: Age less than 18 years Deep and intramuscular lipoma Diffuse lipoma Infection of overlying skin Pregnancy and lactation Ongoing anticoagulant therapy Known case of DIabetes Sensitivity to component of injection immunocompromised patient

Design outcomes

Primary

MeasureTime frame
90 percent reduction in the volume of lipoma in the injection arm as compared to surgical excisionTimepoint: 12 weeks

Secondary

MeasureTime frame
To compare patient satisfaction score between the intervention & comparator groupTimepoint: 12 weeks;To compare the cosmesis between the intervention & comparator group Timepoint: 12 weeks

Countries

India

Contacts

Public ContactDr Monika Gureh

All India Institute of Medical Sciences, Bhubaneswar

halderhrithiwish@gmail.com9729061107

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026