Comparing Probiotic Paste and Antibiotic Strips with Deep Cleaning for Treating Gum Disease

Comparative evaluation of locally delivered probiotic paste and tetracycline fibres as an adjunct to scaling and root planing in treating chronic periodontitis: A split mouth clinical trial - NIL

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/05/087682

Enrollment

Registered

2025-05-27

Start date

Unknown

Completion date

Unknown

Last updated

2025-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: Probiotic Paste as a Local Drug Delivery as an adjunct to Scaling and Root Planing in treating Chronic Periodontitis: Probiotic Paste as a Local Drug Delivery as an adjunct to Scaling a

Eligibility

Inclusion criteria

Inclusion criteria: Chronic periodontitis patient with Probing depth more than or equal to 4mm and less than or equal to 6mm No history of periodontal therapy 6 months prior to the study No usage of antibiotics in the preceding 6 months of study Both genders

Exclusion criteria

Exclusion criteria: Patient suffering from forms of aggressive periodontitis Immunocompromised patient Pregnant and lactating females Patient suffering from any inflammatory changes Alcoholics Patient with uncontrolled systemic disease

Design outcomes

Primary

Measure	Time frame
Parameters measured Probing depth clinical attachement level Plaque index Bleeding indexTimepoint: Baseline 1st,3rd and 6 months	—

Secondary

Measure	Time frame
To evaluate & compare the efficacy of locally delivered probiotic paste & tetracycline fiber as an adjunct to scaling & root planning in patients with chronic periodontitis. To assess & evaluate the adjunctive effects of locally delivered probiotic paste & tetracycline fibers on clinical parameters Pocket Probing Depth Clinical attachment level Bleeding index Plaque indexTimepoint: Baseline 1st,3rd & 6 months	—

Measure

Time frame

To evaluate & compare the efficacy of locally delivered probiotic paste & tetracycline fiber as an adjunct to scaling & root planning in patients with chronic periodontitis. To assess & evaluate the adjunctive effects of locally delivered probiotic paste & tetracycline fibers on clinical parameters Pocket Probing Depth Clinical attachment level Bleeding index Plaque indexTimepoint: Baseline 1st,3rd & 6 months

—

Countries

India

Contacts

Public ContactPriya Tomar

ITS Dental College hospital and Research Centre

hod.perio.gn@its.edu.in9958543469

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026