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IN THIS TRIAL, I WILL BE COMPARING TWO DRUGS: MAGNESIUM SULFATE AND DEXMEDETOMIDINE FOR CONTROLLED HYPOTENSION IN ENT SURGERY

COMPARISON OF INTRA VENOUS MAGNESIUM SULPHATE VERSUS DEXMEDETOMIDINE IN CONTROLLED HYPOTENSION ON FESS: A RANDOMISED DOUBLE-BLIND STUDY - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/05/087681
Enrollment
60
Registered
2025-05-27
Start date
Unknown
Completion date
Unknown
Last updated
2025-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Group D- Dexmedetomidine: Group D- Dexmedetomidine 1 g/kg diluted in 100 ml of 0.9% normal saline administered over 10 min was given as a loading dose followed by infusion at 1 g/kg/h

Sponsors

JLN medical college
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1)Patients of either sex scheduled to undergo elective surgical procedure FESS under general anesthesia and endotracheal intubation. 2)Patients of ASA grade 1 and II. 3)Patient willing to give the consent.

Exclusion criteria

Exclusion criteria: 1)Patients with history of known allergy to study drugs. 2)History of consumption of antihypertensive drugs, sedatives, Hypnotics and antidepressants preoperatively. 3)Pre-existing cardiovascular disease, significant respiratory, renal and hepatic disorder. 4)History of drugs or alcohol abuse. 5)Pregnant and lactating patients

Design outcomes

Primary

MeasureTime frame
To assess and compare the haemodynamic parameters like heart rate, systolic blood pressure, diastolic blood pressure and mean arterial blood pressure from baseline to different time intervals in both groups.Timepoint: Baseline

Secondary

MeasureTime frame
1)To assess and compare Surgeon Satisfaction Score. 2)To assess and compare proportion of patients developing any side effects. 3)To compare Ramsay Sedation Score in post operative period. 4)To evaluate and compare Modified Aldrete Score in post operative period. 5)To evaluate 24 hrs Analgesic consumption in both group. Timepoint: Baseline

Countries

India

Contacts

Public ContactDR VEENA MATHUR

Jawahar lal neharu medical college

veenamathur41@gmail.com9460517947

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026