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Laser therapy for Periodontitis.

Effect of Adjunctive Low level laser Therapy on GCF levels of tissue Plasminogen Activator and Periodontal Inflammatory Burden in Periodontitis. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/05/087657
Enrollment
30
Registered
2025-05-26
Start date
Unknown
Completion date
Unknown
Last updated
2025-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: Scaling and root planing followed by low level laser therapy: Recording of clinical parameters,calculation of PISA and collection of GCF sample at Baseline and 3 months followup. Two s

Sponsors

RGUHS Research Grant
Lead Sponsor
KLE Societys Institute of Dental Sciences
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: Patients of both genders diagnosed with generalised periodontitis stage 3 grade B, in the age group of 30 to 50 years with good systemic health. Presence of a minimum of 20 teeth.

Exclusion criteria

Exclusion criteria: Patients who underwent periodontal therapy during the previous 6 months of commencement of the study. Subjects on antibiotics or immunosuppressant medication 6 months prior to the study. Chronic Smokers, Alcoholics, Smokeless tobacco users. Subjects with acute illnesses/acute intraoral lesions. Pregnant subjects. Medically compromised subjects.

Design outcomes

Primary

MeasureTime frame
Decrease in the Gingival Crevicular Fluid levels of Tissue Plasminogen Activator following application of Low Level Laser Therapy along with Scaling and Root Planing compared to Scaling and Root Planing alone.Timepoint: Baseline and 3 months

Secondary

MeasureTime frame
Periodontal Inflamed Surface Area (PISA) Probing Pocket Depth (PPD) Clinical Attachment Level (CAL) Location of Gingival Margin (LGM) No. of Sites with Bleeding on Probing (BOP) Timepoint: Baseline and 3 months

Countries

India

Contacts

Public ContactDr Amruta Prakash Koparde

KLE Societys Institute of Dental Sciences

drveenahr@gmail.com9480516011

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026