Study to investigate the use of tranexamic acid infiltration during liposuction in male patients with enlarged breast to see if it reduces blood loss during surgery

A Randomized trial to investigate the use of Tranexamic Acid infiltration during liposuction in Gynaecomastia to reduce blood loss - NIL

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/05/087650

Enrollment

Registered

2025-05-26

Start date

Unknown

Completion date

Unknown

Last updated

2025-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N62- Hypertrophy of breast

Interventions

Intervention1: tumescent infiltration with Tranexamic acid: During Gynaecomastia surgery, local infiltration of tumescent solution WITH tranexamic acid will be done during liposuction and if there is

Eligibility

Inclusion criteria

Inclusion criteria: 1)Patients with bilateral gynaecomastia. 2)Patients with Body mass index between 18.5 and 29.9 kg/m2

Exclusion criteria

Exclusion criteria: Patients with abnormal coagulation profile (according to American Society of Anesthesiologists (ASA) guidelines for preoperative preparation of surgical patients). Patients who are receiving treatment for known hyper-coagulable state. Patients with history of cardiac disease or thromboembolic events. Patients with known allergy to tranexamic acid.

Design outcomes

Primary

Measure	Time frame
1)Volume of blood loss in lipoaspirate on the day of surgery. blood loss in lipoaspirate(ml) = infranatant volume + (0.16 supranatant volume) patient s hematocrit hematocrit of lipoaspirate . 2) Drop in Haematocrit :Haematocrit will be requested on Post-op day 1 and compare both the groups to see difference in reduction of haematocrit. 3) Degree of Bruising: On Post-op day 1, Patients will also be assessed for the degree of bruising using a bruising scaleTimepoint: 1)Volume of blood loss in lipoaspirate on the day of surgery.Blood loss in lipoaspirate(ml) = infranatant volume + (0.16 supranatant volume) patient s hematocrit hematocrit of lipoaspirate . 2) Drop in Haematocrit :Haematocrit will be requested on Post-op day 1 and compare both the groups to see difference in reduction of haematocrit. 3) Degree of Bruising: On Post-op day 1, Patients will also be assessed for the degree of bruising using a bruising scale	—

Measure

Time frame

1)Volume of blood loss in lipoaspirate on the day of surgery. blood loss in lipoaspirate(ml) = infranatant volume + (0.16 supranatant volume) patient s hematocrit hematocrit of lipoaspirate . 2) Drop in Haematocrit :Haematocrit will be requested on Post-op day 1 and compare both the groups to see difference in reduction of haematocrit. 3) Degree of Bruising: On Post-op day 1, Patients will also be assessed for the degree of bruising using a bruising scaleTimepoint: 1)Volume of blood loss in lipoaspirate on the day of surgery.Blood loss in lipoaspirate(ml) = infranatant volume + (0.16 supranatant volume) patient s hematocrit hematocrit of lipoaspirate . 2) Drop in Haematocrit :Haematocrit will be requested on Post-op day 1 and compare both the groups to see difference in reduction of haematocrit. 3) Degree of Bruising: On Post-op day 1, Patients will also be assessed for the degree of bruising using a bruising scale

—

Secondary

Measure	Time frame
patients will be assessed for any postoperative complications including hematoma, seroma, or skin complicationsTimepoint: at post-operative day-5 and weekly upto 6 weeks	—

Countries

India

Contacts

Public ContactShruti K Somani

All India Institute Of medical sciences, New Delhi

shivangisaha@gmail.com9968969174

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026