Comparative Healing Outcomes of Knotless Barbed Sutures vs resorbable Sutures in removal of Impacted Third Molar of lower jaw

Knotless Barbed Suture Versus Polyglactin Suture In Healing Of Extraction Socket After Impacted Mandibular Third Molar Surgery : A Prospective, Comparative, Randomized, Split Mouth Study - NIL

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/05/087644

Enrollment

Registered

2025-05-26

Start date

Unknown

Completion date

Unknown

Last updated

2025-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Knotless barbed suture: Surgical removal of the impacted teeth will be performed under local anaesthesia. Preoperative maximum inter-incisal opening and Preoperative swelling will be no

5% povidone iodine solution will be used for site preparation and 2% lignocaine hydrochloride with 1:80,000 adrenaline will be administered as inferior alveolar, lingual and buccal nerve blocks. Conv

5% povidone iodine solution will be used for site preparation and 2% lignocaine hydrochloride with 1:80,000 adrenaline will be administered as inferior alveolar, lingual and buccal nerve blocks. Conve

Eligibility

Inclusion criteria

Inclusion criteria: Patients with bilaterally impacted mandibular third molars require surgical removal. Patients who fall within the ASA 1 (American Society of Anaesthesiology) classification Patients with similar difficulty indexes of impacted teeth- Mesioangular, Class I, Position A of Pell and Gregory classification.

Exclusion criteria

Exclusion criteria: Patients with poor oral hygiene. Pregnant or lactating women. Patients who declined participation.

Design outcomes

Primary

Measure	Time frame
Primary outcome is to compare performance of knotless barbed sutures against polyglactin sutures in surgical wound closure in the removal of bilateral, similarly impacted mandibular third molars and to access Pain level, Post-operative swelling, Maximum Inter-incisal opening, Wound closure timeTimepoint: The estimated time may range upto 7 days.	—

Secondary

Measure	Time frame
Secondary outcome is to compare performance of knotless barbed sutures against polyglactin sutures in surgical wound closure in the removal of bilateral, similarly impacted mandibular third molars and to access Pain level, Post-operative swelling, Maximum Inter-incisal opening, Wound closure timeTimepoint: The estimated time may range upto 7 days.	—

Countries

India

Contacts

Public ContactDr Madan Mishra

Sardar Patel Post Graduate Institute of Dental and Medical Sciences

mm.15mds@gmail.com9565740127

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026