Skip to content

BEDSIDE ECHOCARDIOGRAPHIC ASSESSMENT OF HEMODYNAMIC PARAMETERS IN CHILDREN WITH SEPTIC SHOCK AND ITS IMPACT ON CLINICAL OUTCOMES

POINT-OF-CARE ECHOCARDIOGRAPHIC HEMODYNAMIC CHARACTERIZATION OF PEDIATRIC SEPTIC SHOCK: A PROSPECTIVE OBSERVATIONAL STUDY (EPICS STUDY) - EPICS Study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2025/05/087595
Enrollment
100
Registered
2025-05-26
Start date
Unknown
Completion date
Unknown
Last updated
2025-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I958- Other hypotension

Interventions

None listed

Sponsors

PGIMER Chandigarh
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Age group: 3 months-12 years Admitted to PICU with diagnosis of fluid refractory septic shock.

Exclusion criteria

Exclusion criteria: Congenital or acquired heart disease including valvular heart disease and dilated cardiomyopathy. Poor window limiting image acquisition e.g. subcutaneous emphysema, abdominal surgery, thoracic surgery. Moribund state or anticipated death within 24 hours. Post-cardiac arrest state Denied consent.

Design outcomes

Primary

MeasureTime frame
To evaluate point-of-care echocardiographic in hemodynamic characterization of children with septic shock.Timepoint: Within 6 hours of labeling a child as fluid refractory septic shock

Secondary

MeasureTime frame
Additional interventions instituted after the point-of-care echocardiography. Timepoint: Within 6-12 hours of enrolment;Response to additional interventions instituted after the point-of-care echocardiography. Timepoint: Within 6-12 hours of enrolment;Difference in point-of-care echocardiography findings among survivors & non-survivors. Timepoint: Till discharge from PICU or death;Cardiac biomarkers (CK-MB, cTnT, & proBNP) at time of enrolment. Timepoint: Within 6 hours of enrolment

Countries

India

Contacts

Public ContactSuresh Kumar

PGIMER Chandigarh

mjshree@hotmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026