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Study To See How A Mix Of Patients Own Blood And Bone-Like Material Helps Heal Bone Loss In Adults With Gum Disease

EVALUATING THE IMPACT OF ADVANCED PLATELET RICH FIBRIN BLOCK AND NANOHYDROXYAPATITE GRAFT IN TISSUE REGENERATION OF PERIODONTAL INTRA-BONY DEFECTS A CLINICO-RADIOGRAPHIC STUDY - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/05/087590
Enrollment
42
Registered
2025-05-26
Start date
Unknown
Completion date
Unknown
Last updated
2025-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: Advanced Platelet Rich Fibrin Block: It combines the fragments of L-PRF. i-PRF and bone graft material to create a cohesive matrix for filling bone defects 12 months Control Interventio

Sponsors

Institute Of Dental Sciences, Bareilly
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients with Stage-II and Stage-III periodontitis Presence of two or three-walled bony defect with a depth of more than three millimeters, using cone beam computed tomography Patients having platelet count within the normal range

Exclusion criteria

Exclusion criteria: Systemically compromised patients Pregnant and lactating females Smokers and alcoholics Patients who underwent periodontal surgery in past six months Patients with coagulation disorders

Design outcomes

Primary

MeasureTime frame
Defect Resolution Mean gain in bone volume Bone fillTimepoint: Baseline and 9 months—

Secondary

MeasureTime frame
Relative attachment level Probing pocket depthTimepoint: Baseline and 9 months—

Countries

India

Contacts

Public ContactDr. Manvi Chandra Agarwal

Institute Of Dental Sciences Bareilly

agarwalmanvi25@gmail.com9457540800

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026