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EFFECT OF PROPHYLACTIC INTRAMUSCULAR GLYCOPYRROLATE ON HEMODYNAMICS AND VASOPRESSOR REQUIREMENT AND INTRAOPERATIVE NAUSEA AND VOMITING IN PATIENTS UNDERGOING LSCS UNDER SPINAL ANAESTHESIA. A PROSPECTIVE RANDOMIZED STUDY

EFFECT OF PROPHYLACTIC INTRAMUSCULAR GLYCOPYRROLATE ON HEMODYNAMICS AND VASOPRESSOR REQUIREMENT AND INTRAOPERATIVE NAUSEA AND VOMITING IN PATIENTS UNDERGOING LSCS UNDER SPINAL ANAESTHESIA. A PROSPECTIVE RANDOMIZED STUDY - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/05/087587
Enrollment
60
Registered
2025-05-26
Start date
Unknown
Completion date
Unknown
Last updated
2025-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O94-O9A- Other obstetric conditions, not elsewhere classified

Interventions

Intervention1: IN THIS STUDY WE HAVE ADMINISTERED 0.2 MG INJECTION GLYCOPYRROLATE IN LEFT DELTOID 15 MINUTES BEFORE SPINAL ANAESTHESIA IN 30 PATIENTS AND 0.9% NORMAL SALINE 1 ML IN LEFT DELTOID 15 MIN

Sponsors

DR MANORMA YADAV
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: PATIENTS UNDERGOING LSCS UNDER SPINAL ANAESTHESIA GIVING CONSENT TO PARTICIPATE IN STUDY AND AGE GROUP BETWEEN 21 TO 35 YEARS WITH ASA STATUS I AND II

Exclusion criteria

Exclusion criteria: PATIENTS NOT GIVING CONSENT AGE MORE THAN 50 YEARS HEIGHT LESS THAN 150 CM ASA GRADE III AND IV KNOWN FETAL ABNORMALITY HYPERTENSIVE DISORDER TWIN PREGNANCY CONTRAINDICATIONS TO SPINAL ANAESTHESIA

Design outcomes

Primary

MeasureTime frame
PROPHYLACTIC INTRAMUSCULAR GLYCOPYRROLATE 0.2 mg MAY SIGNIFICANTLY REDUCE THE INCIDENCE OF HYPOTENSION DURING SPINAL ANAESTHESIA WHEN COMPARED WITH THE CONTROL GROUP.Timepoint: 15 mintes—

Secondary

MeasureTime frame
PROPHYLACTIC INTRAMUSCULAR GLYCOPYRROLATE 0.2 MG DOES NOT CAUSES MAJOR ADVERSE EFFECTSTimepoint: 120 MINUTES—

Countries

Japan

Contacts

Public ContactDR SUMAN GUPTA

GAJRA RAJA MEDICAL COLLEGE GWALIOR

sumangupta02@rediffmail.com9981962454

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026