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This study looks at people who had their thyroid removed and low parathyroid hormone levels after surgery. It compares giving calcium and vitamin D supplements to everyone right away versus only to those with symptoms, aiming to find which approach better supports recovery and hormone balance.

Effect of calcium and vitamin D supplementation routinely vs exclusively in symptomatic patient on postoperative parathyroid hormone levels in total thyroidectomy patients with low parathyroid hormone level post operatively-An Open-Label Randomized Controlled Trial - nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/05/087585
Enrollment
88
Registered
2025-05-26
Start date
Unknown
Completion date
Unknown
Last updated
2025-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C73- Malignant neoplasm of thyroid gland

Interventions

Intervention1: blood draw for testing serum calcium and parathyroid hormone level and vit-D.: in patient undergoing total thyroidectomy will check PTH and calcium and vitamin-D level on POD-0 30 and

Sponsors

JIPMER INTRAMURAL RESEARCH FUND
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients more than 18yrs of age undergoing total thyroidectomy with skin closure PTH level more than 15 pg/ml and pre-operative serum calcium more than 10.5mg/dl.

Exclusion criteria

Exclusion criteria: - patient with pre-operative serum calcium more than 10.5 mg/dl. - Patients with coexisting parathyroid pathology. - Chronic renal impairment - Patients on oral calcium and calcitriol supplementation. - Pregnant and lactating females - unwilling to participate.

Design outcomes

Primary

MeasureTime frame
To study the effect of calcium and vitamin D supplementation given routinely as compared to exclusively in symptomatic patients on post-operative parathyroid hormone (PTH) levels (POD 0, 1st month and 3rd months) in total thyroidectomy patients with low parathyroid hormone level post operativelyTimepoint: At post operative day 0 , post operative day 30 and 90—

Secondary

MeasureTime frame
To study the effect of calcium and vitamin D supplementation given routinely as compared to exclusively in symptomatic patients on calcium, magnesium and phosphorus levelsTimepoint: 3 months;To study the effect of calcium and vitamin D supplementation given routinely as compared to exclusively in symptomatic patients on post op Serum Vitamin D levels in patients with Vitamin D deficiencyTimepoint: 3 months—

Countries

India

Contacts

Public ContactELAMURUGAN TP

jawarharlal institute of postgraduate medical education and research (JIPMER)

elamurugantp@gmail.com9443648918

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026