Health Condition 1: M321- Systemic lupus erythematosus withorgan or system involvement
Conditions
Interventions
Intervention1: Yoga group: Structured yoga protocol (of 40 minutes duration) will be implemented for all subjects in the group. and subsequent sessions can be attended online. They should attend at l
Sponsors
PGIMER
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients fulfilling 2019 ACR/EULAR criteria for SLE. 2. Active SLE as indicated by SLEDAI more than or equal to 1. 3. Onset of disease within the last 5 years. 4. Consenting to participate in the study.
Exclusion criteria
Exclusion criteria: 1. Severe organ manifestations like heart failure, respiratory failure, and renal failure requiring hemodialysis. 2. Presence of hypotension, shock, or severe sepsis. 3. Presence of altered mental status or unconsciousness at the time of recruitment. 4. Presence of neuropsychiatric manifestations requiring the use of antidepressants and antipsychotics. 5. Patients who are physically unfit to do yoga due to conditions like fractures, hemiparesis, foot drop, etc. 6. Severe anemia, hemoglobin less than 8g%, or severe thrombocytopenia, less than 20,000/cumm. 7. Pregnant women and lactating mothers. 8. Patients who have been actively practicing yoga in the last three months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in quality of life, as measured by the SLEQoL questionnaireTimepoint: 12 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| Change in SLEDAITimepoint: 12 weeks;Change in ESR, CRP, C3 and C4 levelsTimepoint: 12 weeks;Change in Depression, Anxiety, and Stress Scale- 21 (DASS-21) scoreTimepoint: 12 weeks;Change in serum levels of IP-10, MCP-1, and IL-6Timepoint: 12 weeks | — |
Countries
India
Contacts
Public ContactGSRSNK Naidu
PGIMER, Chandigarh
Outcome results
None listed