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A study to understand the stressful memories of ICU treatment and the experience of feeling awake after receiving muscle-paralysing medications in survivors of critical illness.

Awareness with paralysis and stressful memories in critical illness survivors - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2025/05/087548
Enrollment
153
Registered
2025-05-26
Start date
Unknown
Completion date
Unknown
Last updated
2025-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: R419- Unspecified symptoms and signs involving cognitive functions and awareness

Interventions

Intervention1: Nil: Nil Intervention2: Nil: Nil

Sponsors

Midhun Mathews
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Adults, 18 years or older 2.All patients who require mechanical ventilation through an endotracheal tube. 3.Patients who receive neuromuscular blockers at any time during ICU stay(for tracheal intubation or in the post-intubation phase of care).

Exclusion criteria

Exclusion criteria: 1.Death before discontinuation of mechanical ventilation. 2.Acute or chronic neurologic injury with deficit that prevents assessment of awareness with paralysis (i.e., stroke, intracranial hemorrhage, traumatic brain injury, cardiac arrest, advanced dementia, severe critical illness neuropathy) 3.Tracheostomized patients. 4.Transfer to another facility. 5.Unable to answer the questionnaire. 6.Patients who don t provide consent. 7.Patients who don t speak and understand English, Telugu, Tamil, Kannada, Hindi, Malayalam

Design outcomes

Primary

MeasureTime frame
1.To estimate the prevalence of awareness with paralysis in critically ill patients. 2.To predict the risk factors for AWP and stressful memory. Timepoint: At baseline

Secondary

MeasureTime frame
1.To evaluate the recall of ICU memories and stressful memories, recall of events and patient experience among patients receiving mechanical ventilation. 2.To analyse the potential relieving factors of stressful memory of ICU stay. 3.To estimate the prevalence of posttraumatic stress in patients after hospital discharge. 4.To predict the risk factors for PTSD.Timepoint: 1,2 and 4 are done at baseline. 3 is done at 4 and 8 weeks after discharge.

Countries

India

Contacts

Public ContactDr Natesh Prabu R

St. Johns Medical College Hospital, Bangalore

natesh.prabu@stjohns.in9969523803

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026