Studying Different Ways to Plan Surgery for Breast Cancer Patients Who Responded Well to Chemotherapy

Comprasion of methods of margin delineation for vaccum-assisted excision in Breast cancer patients with radilogical complete response post neoadjuvant chemotherapy - NIL

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/05/087545

Enrollment

Registered

2025-05-26

Start date

Unknown

Completion date

Unknown

Last updated

2025-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C508- Malignant neoplasm of overlappingsites of breast

Interventions

Intervention1: Bracketing: Marker clip would be inserted at edge of mass pre-chemotherapy to mark margin of vacuum excision Control Intervention1: Standard technique: Clip placed at the centre of the

Eligibility

Inclusion criteria

Inclusion criteria: Patients with breast cancer who have undergone NACT and have a complete response on mammography and ultrasound. Patients in whom breast localisation clip has been placed.

Exclusion criteria

Exclusion criteria: Patients with extensive intraductal components on initial biopsy. Patients with extensive microcalcifications on initial mammography in addition to mass. Patients without accurate localisation by means of a clip, in whom mass cannot be accurately localised on mammogram after NACT.

Design outcomes

Primary

Measure	Time frame
Feasibility, concordance with surgical pathologyTimepoint: Time point is at the time of surgery in both cases, which is atleast 2 weeks after completion of NACT	—

Secondary

Measure	Time frame
n/aTimepoint: n/a	—

Countries

India

Contacts

Public ContactDr Krithika Rangarajan

AIIMS, Delhi

krithikarangarajan@aiims.edu9810488850

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026