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A Study to compare the postoperative complications in patients undergoing abdominal surgeries where patients own blood will be transfused back when needed during the surgery compared to the standard of care.

Impact of Acute Normovolemic Hemodilution on Postoperative complications in patients undergoing Elective Abdominal surgery: A Randomized Controlled trial. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/05/087513
Enrollment
130
Registered
2025-05-23
Start date
Unknown
Completion date
Unknown
Last updated
2025-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C15-C26- Malignant neoplasms of digestive organs Health Condition 2: K80-K87- Disorders of gallbladder, biliary tract and pancreas Health Condition 3: K70-K77- Diseases of liver Health Condition 4: K20-K31- Diseases of esophagus, stomach and duodenum Health Condition 5: K55-K64- Other diseases of intestines Health Condition 6: K62- Other diseases of anus and rectum

Interventions

Intervention1: Acute Normovolemic Hemodilution: Withdrawing 1 unit of blood - 350 ml from the patient before surgery after induction of anaesthesia and transfusing back to the same patient when indica

Sponsors

JIPMER Intramural Research Fund
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: PATIENTS AGED MORE THAN OR EQUAL TO 18 YEARS UNDERGOING ELECTIVE ABDOMINAL SURGERY

Exclusion criteria

Exclusion criteria: Patients with hemoglobin less than 11 gram per decilitre. Patients undergoing elective Abdominal surgery where significant blood loss is not expected which requires a transfusion during surgery. Presence of clinically significant cardiac, pulmonary or renal disease. Patient with severe hypertension.

Design outcomes

Primary

MeasureTime frame
To compare the rates of postoperative complications in patients undergoing elective abdominal surgery following acute normovolemic hemodilution with the standard of careTimepoint: 30 DAYS—

Secondary

MeasureTime frame
To compare the perioperative inflammatory markers such as WBCs & hs-CRP in Patients undergoing elective abdominal surgery following acute normovolemic hemodilution with the standard of careTimepoint: Preoperative, Postoperative day 1;To compare the blood transfusions in patients undergoing elective abdominal surgery following acute normovolemic hemodilution with the standard of careTimepoint: During surgery, during hospital stay till discharge of patient;To prepare the Maximum Surgical Blood Ordering Schedule for various abdominal surgeries in the departmentTimepoint: 2 years during study period;To compare the perioperative serum albumin in Patients undergoing elective abdominal surgery following acute normovolemic hemodilution with the standard of careTimepoint: Preoperative, Postoperative day 1;To compare the incidence of transfusion reactions in patients undergoing elective abdominal surgery following acute normovolemic hemodilution with the standard of careTimepoint: 2 Years during study period;To compare the 30 day Mortality rate in patients undergoing elective abdominal surgery following acute normovolemic hemodilution with the standard of careTimepoint: Postoperative day 0 to Postoperative day 30—

Countries

India

Contacts

Public ContactVishnu Prasad N R

Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry - 605006

vishnupnr@yahoo.com9442233487

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026