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Exploring Spinal Cord Nerve Signal Changes During Surgery for Children with Tethered Spinal Cords: A study looking at the causes and management.

Incidence of and Factors Associated with Intraoperative Neurophysiological Monitoring Signal Change/Loss and Its Management in Children Undergoing Neurosurgical Procedures for Tethered Cord Syndrome: A Prospective, Observational Study - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2025/05/087462
Enrollment
114
Registered
2025-05-23
Start date
Unknown
Completion date
Unknown
Last updated
2025-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: G958- Other specified diseases of spinalcord

Interventions

Intervention1: Nil: Nil Intervention2: Nil: Nil

Sponsors

Christian Medical College Vellore
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All patients below the age of 18 years undergoing detethering for Tethered Cord Syndrome under IONM will be included

Exclusion criteria

Exclusion criteria: Age more than 18years Refusal of Consent by the parents Patients in whom baseline signal was not obtained

Design outcomes

Primary

MeasureTime frame
To assess the incidence of significant signal change or loss during intraoperative neurophysiological monitoring in children presenting for neurosurgical procedures for tethered cord syndromes and to describe the management strategies for these occurrences.Timepoint: Postoperative days 0, 24 hours and 7 days

Secondary

MeasureTime frame
1. To estimate the percentage of significant intraoperative neurophysiological monitoring (IONM) signal changes or losses during neurosurgical procedures for tethered cord syndromes. 2. To assess the management strategies of significant IONM signal change or losses during neurosurgical procedures for tethered cord syndrome. 3. To identify the factors associated with significant IONM signal changes or losses during intraoperative neurophysiological monitoring during neurosurgical procedures for tethered cord syndrome. 4. To describe the temporal evolution of the changed signal and correlate it with changes in surgical or anaesthetic strategies. 5. To describe the clinical outcomes in patients with significant change/loss of signal during intraoperative neurophysiological monitoring 6. To observe the incidence of complications associated with intraoperative neurophysiological monitoring. Timepoint: Postoperative days 0, 24 hours and 7 days

Countries

India

Contacts

Public ContactJAMES THAPA MAGAR

Department of Neuroanaesthesiology

karen@cmcvellore.ac.in9442631528

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026