Clinical Efficacy of Plasma Activated Dental Implants in Individuals with Vitamin D Deficiency/Insufficiency - A Randomized Controlled Clinical Trial

Clinical Efficacy of Plasma Activated Dental Implants in Individuals with Vitamin D Deficiency/Insufficiency - A Randomized Controlled Clinical Trial - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/05/087428

Enrollment

Registered

2025-05-22

Start date

Unknown

Completion date

Unknown

Last updated

2025-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Dental Implant Placement: Plasma Activated Dental Implants in individuals with Vitamin D deficiency/ insufficiency Duration of intervention : Years: 1 Months:6 (August 2025 to January

Eligibility

Inclusion criteria

Inclusion criteria: Systemically healthy individuals between 20- 45 years of age Both gender- male and female. Vitamin D deficient less than 20 ng per ml or Insufficient 20-29 ng per ml (as per ICMR guidelines) Partially edentulous with minimum of one missing tooth in either maxillary or mandibular arches Adequate bone height and width in the edentulous site for placement of a regular dental implant. Restoration of implant should be possible with adequate occlusal clearance.

Exclusion criteria

Exclusion criteria: Individuals with habits such as smoking Individuals taking calcium/ vitamin D supplementation Individuals with other diseases which affect the bone metabolism and impair osseointegration Individuals who are on glucocorticoid medication. Pregnant or lactating individuals. Individuals undergoing orthodontic therapy Completely edentulous patients.

Design outcomes

Primary

Measure	Time frame
Plasma activated implants will demonstrate better implant stability in Vitamin D deficient/insufficient individuals as compared to Non-activated SLA implant surfaces.Timepoint: baseline, 4 weeks, 3 months , 6 months	—

Secondary

Measure	Time frame
Plasma activated implants will demonstrate lesser marginal bone loss in Vitamin D deficient/insufficient individuals as compared to Non-activated SLA implant surfaces.Timepoint: baseline, 3 months, 6 months & one year	—

Countries

India

Contacts

Public ContactDr Arvinda Siva J

Sri Ramachandra Institute of Higher Education and Research

vamsilavu@sriramachandra.edu.in9841326869

Outcome results