FindTrial
Sign In

Effect of intravenous lignocaine and opoid on polytrauma patients admitted in ICU and effect of both on their inflammation status,and other blood biomarkers and their side effects

Assessment of effects of iv lignocaine with IV OPOIDS vs IV opoid PLAIN over polytRauma stress response - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/05/087403
Enrollment
60
Registered
2025-05-22
Start date
Unknown
Completion date
Unknown
Last updated
2025-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: R068- Other abnormalities of breathing Health Condition 2: R068- Other abnormalities of breathing

Interventions

Intervention1: IV LOXICARD: IV LOXICARD INFUSION IN ALLOWABLE DOSE Intervention2: IV Lignocaine with iv Fentanyl: lignocaine 1.5 mg followed by IV lignocaine infusion in a dose of 1.5mg/kg/hr and dos

Sponsors

Shivam Rai
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Age 18 to 85 years informed written consent A person who has suffered multiple traumatic injury in their body as a result of single event

Exclusion criteria

Exclusion criteria: Patient with relevant drug allergy Patient with opoid dependence Patients who refused to participate in studies

Design outcomes

Primary

MeasureTime frame
effects of IV lignocaine combined with IV opioids compared to IV opioids alone on the physiological and biochemical stress (e.g., IL-6, LDH)response in polytrauma patientsTimepoint: 0H HOURS, 8 HOURS ,24 HOURS, 36 HOURS—

Secondary

MeasureTime frame
1.Pain Control: Whether IV Lignocaine provides superior analgesia compared to opioid-only treatment. 2.Opioid Consumption: Whether IV Lignocaine reduces opioid requirements, thereby minimizing opioid-related side effects. Timepoint: from time of admission till 36 hours—

Countries

India

Contacts

Public ContactShivam Rai

GSVM Medical College Kanpur

anil_16021976@rediffmail.co.in9336107410

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026