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To study sweat response in patients of single limb wasting

To study the involvement of autonomic nervous system in monomelic amyotrophy by computing the sympathetic skin response - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2025/05/087366
Enrollment
36
Registered
2025-05-22
Start date
Unknown
Completion date
Unknown
Last updated
2025-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: G958- Other specified diseases of spinalcord

Interventions

Intervention1: Nil: Nil Intervention2: Nil: Nil Intervention3: Nil: Nil Intervention4: Nil: Nil Intervention5: Nil: Nil Intervention6: Nil: Nil

Sponsors

AIIMS Bhubaneswar
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1) Each patient meeting the criteria for monomelic amyotrophy if their clinical characteristics and EMG results suggested lower motor neuron involvement limited to one upper limb 2) The affected hand or hands may exhibiting Irregular coarse tremors (polyminimyoclonus) in the fingers 3) Electromyography demonstrating persistent denervation in the affected muscles either clinically or subclinically 4) Age 15 to 65 years

Exclusion criteria

Exclusion criteria: 1) Patients with symmetrical limb involvement 2) Patients with History of Neck Trauma or Neck Surgery 3) Patients younger than 15 years 4) Patients with known CV junction anomalies 5) ) Patient having monomelic amyotrophy as a part of other Anterior Horn Cell Diseases like ALS, post-polio residual paresis 6) Patients with the Conduction block detected by NCS

Design outcomes

Primary

MeasureTime frame
Autonomic nervous system involvement in Hirayama DiseaseTimepoint: Baseline

Secondary

MeasureTime frame
TMS induced Motor evoked potential in Hirayama DiseaseTimepoint: Baseline

Countries

India

Contacts

Public ContactDr Mayur C M

AIIMS Bhubaneswar

bhoisanjeev@gmail.com9919787978

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026