To evaluate the bone fill after placing Erythropoietin gel in combination with an allograft in some patients and compare its effects with allografts alone

Comparative evaluation of Demineralised Freeze Dried Bone Allograft with and without Erythropoietin gel in the surgical management of three walled intrabony periodontal defects A Randomized Controlled Clinical Study - Nil

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/05/087355

Enrollment

Registered

2025-05-22

Start date

Unknown

Completion date

Unknown

Last updated

2025-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K05- Gingivitis and periodontal diseases

Interventions

Intervention1: Comparative evaluation of Demineralised Freeze-Dried Bone Allograft with Erythropoietin gel in the surgical management of three walled intrabony periodontal defects: Erythropoietin gel

Eligibility

Inclusion criteria

Inclusion criteria: 1.Both genders within age range of 20-50 years. 2.Patients diagnosed with periodontitis (Stage III). 3.Test site criteria: probing pocket depth >=6mm and CAL >=3mm. All these criteria will be determined after phase I conventional periodontal therapy. 4.Patients with three walled intrabony defect. 5.Systematically healthy patients. 6.Ability to attend the treatment sessions and comply with its procedures, recall visits and oral hygiene protocol.

Exclusion criteria

Exclusion criteria: 1.Smokers. 2.Pregnant or lactating females. 3.Patients under any medication that affect periodontal healing.

Design outcomes

Primary

Measure	Time frame
Radiographic bone fill obtained in three walled intrabony defects when treated with erythropoietin gel in combination with DFDBATimepoint: Baseline, 3 months and 6 months	—

Secondary

Measure	Time frame
Clinical Attachment Level, Probing Pocket Depth and Horizontal Probing Depth in three walled intrabony defects when treated with erythropoietin gel in combination with DFDBA and DFDBA aloneTimepoint: Baseline, 3 months and 6 months	—

Countries

India

Contacts

Public ContactDr Kamalkishor Mankar

Ranjeet Deshmukh Dental College and Research Centre, Digdoh Hills, Hingna Road, Nagpur

drkamalk@gmail.com9850061038

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026