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Comparing Outcomes of Vital Pulp Therapy in Permanent Molars: Natural vs. Synthetic Biomaterials for Reversible Pulpitis

Outcomes of Vital Pulp Therapy Using Natural and Synthetic Biomaterials in Permanent Molars with Reversible Pulpitis : A Randomised Controlled Study. - nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/05/087321
Enrollment
72
Registered
2025-05-21
Start date
Unknown
Completion date
Unknown
Last updated
2025-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K029- Dental caries, unspecified

Interventions

Intervention1: Acemannan (Group 1),: Acemannan sponge (Group 1) will be then placed over the exposed pulp. Intervention period is for 6 months. Intervention2: Naringenin (Group 2): Naringenin sponge (

Sponsors

None listed

Eligibility

Inclusion criteria

Inclusion criteria: 1.The patients with age group 18-45. 2.The patients who will give written consent. 3.Healthy patient with pin-point exposed mature and vital permanent molars, with caries or accident-induced pulp exposure will be included in the study. 4.Patient having vital molars with deep caries approaching the pulp.

Exclusion criteria

Exclusion criteria: 1.The patient who won t give written consent and show no compliance. 2.The patient with history of systemic disease that interferes with pulp healing. 3.The molars which have clinical signs and symptoms of irreversible pulpitis, e.g., spontaneous throbbing pain, tenderness to percussion, abnormal tooth mobility, swelling, or sinus tract. 4.The molars which show sign of pulp necrosis. 5.Radiographic evidence of internal or external resorption, inter-radicular bone loss, or periapical pathology. 6.The tooth which are non-restorable.

Design outcomes

Primary

MeasureTime frame
No clinical symptoms of pulpitisTimepoint: Baseline , 1 and then 3 months

Secondary

MeasureTime frame
Signs of regeneration are seen.Timepoint: 6 months.

Countries

India

Contacts

Public ContactDr Promila Verma

King Georges Medical University

rakeshanita10@yahoo.in9415281156

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026