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Risk Factors and Serum Survivin Correlation in Acne Scarring: A Biomarker-Based Study

To study the risk factors of acne scarring and its correlation with serum biomarker Survivin. - nil

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2025/05/087300
Enrollment
45
Registered
2025-05-21
Start date
Unknown
Completion date
Unknown
Last updated
2025-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: L700- Acne vulgaris

Interventions

Intervention1: Nil: Nil Intervention2: Nil: Nil

Sponsors

Shanmuga Raju
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients presenting to dermatology OPD with acne of any grade. 2.People who are willing to participate in the study.

Exclusion criteria

Exclusion criteria: 1.Women who have used oral contraception or any other hormonal treatment or anti androgen treatments in the last 3 months. 2. Patients with drug induced acne 3. Those patients not willing for blood investigations.

Design outcomes

Primary

MeasureTime frame
Primary Outcome: Identification of risk factors associated with acne scarring - Assessing the influence of severity, duration, genetic predisposition, environmental triggers, and lifestyle factors on acne scar formation. - Stratifying patients based on Global Acne Grading System (GAGS) scores and Goodman & Baron s Quantitative Scar Scale. - Analyzing the role of serum Survivin levels as a potential biomarker for fibrosis in acne scarring. - Using Chi-square test and multivariate analysis to determine statistical significance of risk factor associations. Timepoint: Single time point: Data collection occurs at the time of enrollment, with no follow-ups

Secondary

MeasureTime frame
A.To assess the levels of Survivin in serum of acne individuals with scarring. B.To look for association of survivin in serum with the severity of acne scarring. C.To grade and compare the risk factors of acne scarring. Timepoint: Single time point: Data collection occurs at the time of enrollment, with no follow-ups

Countries

India

Contacts

Public ContactDr Lekshmi S

Amrita Institute of Medical Sciences

ammaslekshmithun@gmail.com9995656423

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026