Skip to content

Comparing Piezo surgery Alone versus Piezo surgery with Dexamethasone in post operative sequalae following impacted mandibular third molar: A Clinical Trial

COMPARATIVE EVALUATION OF PIEZOSURGERY VERSUS PIEZOSURGERY WITH INTRAMUSCULAR DEXAMETHASONE IN POSTOPERATIVE SEQUELAE IN THE EXTRACTION OF IMPACTED MANDIBULAR THIRD MOLAR: A RANDOMIZED CONTROLLED TRIAL - PIMDEX Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/05/087246
Enrollment
40
Registered
2025-05-21
Start date
Unknown
Completion date
Unknown
Last updated
2025-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: Z768- Persons encountering health services in other specified circumstances

Interventions

Intervention1: Piezo surgery with intramuscular dexamethasone for the impacted mandibular third molar: Study group- in this we will give intramuscular dexamethasone half an hour prior to surgery and w

Sponsors

Dr LATIKA MANGHNANI
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1) Patients between age of 18-45 years of both genders. 2) Patients indicated for surgical removal of impacted mandibular third molar with moderately difficult score as per modified Pederson difficulty index. 3) Healthy patients falling under ASA I and ASA II 4) Subjects able and willing to provide written informed consent and compliant with study procedure

Exclusion criteria

Exclusion criteria: 1. Patients with mouth opening less than 30mm. 2. Patient with allergy with NSAIDS. 3. Patients having history of drug abuse. 4. Patients having any systemic or local immunodeficiency. 5. Patient is under regular analgesics and anti-depressants. 6. Having any blood coagulation impairment. 7. Presence of any acute oral infection. 8. Have been suffering with uncontrolled diabetes or other systemic diseases. 9. Having previous history of radiation therapy in the head and neck region. 10. Having previous history of chemotherapy. 11. Pregnant and nursing women. 12. Soft tissue impactions.

Design outcomes

Primary

MeasureTime frame
1. Pain 2. Facial swelling 3. Trismus 4. Number of rescue analgesics Timepoint: on 1st, 3rd and 7th post operative day

Secondary

MeasureTime frame
any other complication if arise will be notedTimepoint: on 1st, 3rd & 7th post operative day

Countries

India

Contacts

Public ContactDr. Latika manghnani

Geetanjali Dental & Research Institute

drshallu23@yahoo.com9116155666

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026