Health Condition 1: R652- Severe sepsis
Conditions
Interventions
Intervention1: Nil: Nil
Sponsors
Dr Mounika Vadhi Reddy
Eligibility
Inclusion criteria
Inclusion criteria: - All pediatric patients aged more than 28 days (corrected gestational age above 44 weeks) to less than 18 completed years receiving treatment in the participating PICUs at 10 AM on each study day, AND - Having clinician suspected/diagnosed sepsis, both community- and hospital/healthcare acquired, during the 24-hour window from 10 AM the previous day to 10 AM on the study day.
Exclusion criteria
Exclusion criteria: None
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Point prevalence of pediatric sepsis among children admitted to Indian PICUs on pre-defined study days.Timepoint: On pre-defined study days | — |
Secondary
| Measure | Time frame |
|---|---|
| Point prevalence of septic shock among PICU admissions.Timepoint: On pre-defined study days;Distribution of pathogens, frequency and types of antimicrobials and treatments usedTimepoint: On pre-defined study days;28-day all-cause PICU and in-hospital mortality rate among sepsis patientsTimepoint: On day-28 from study day;Median PICU and hospital length of stayTimepoint: On day-28 from study day;Change in functional status from admission to hospital discharge for survivors censored at 28 daysTimepoint: On day-28 from study day;Predictors of mortality, length of stay, and organ dysfunction in pediatric sepsisTimepoint: On day-28 from study day;- Agreement of Phoenix sepsis score with clinician-suspected/diagnosed sepsis and its discriminative ability for key clinical outcomes such as mortality, length of stay and organ dysfunctionTimepoint: On pre-defined study days and On day-28 from study day;Comparison of sepsis prevalence, treatments and outcomes across different geographic regionsTimepoint: On pre-defined study days and On day-28 from study day | — |
Countries
India
Contacts
Public ContactDr Mounika Vadhi Reddy
All India Institute of Medical Sciences, Bibinagar
Outcome results
None listed