study to see the effect of magnesium sulphate on anesthetic drug requirement and pain relive after surgery in patients undergoing craniotomy.

A Randomised controlled prospective study on the effect of magnesium sulphate infusion on total anesthetic requirement and post operative analgesia in craniotomy patients. - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/05/087226

Enrollment

Registered

2025-05-21

Start date

Unknown

Completion date

Unknown

Last updated

2025-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: 8- Other Procedures

Interventions

Intervention1: IV Magnesium sulfate: Patients undergoing craniotomy will receive 30 mg/kg of magnesium sulfate in 100 ml of isotonic saline over 20 min immediately before anesthesia induction, then th

Eligibility

Inclusion criteria

Inclusion criteria: a. Patient undergoing craniotomy b. ASA status I & II c. Patient attendent giving consent

Exclusion criteria

Exclusion criteria: a. In musculo skeletal disorder, geriatric and pediatric patient b. Patients with electrolyte disturbance, those on treatment with calcium channel blocker c. Patients with significant organ dysfunction d. Morbid obese e. Patient attendent consent refusal

Design outcomes

Primary

Measure	Time frame
Anaesthetic requirementTimepoint: Whole intraoperative period	—

Secondary

Measure	Time frame
a. Post operative analgesia requirement b. Intra op hemodynamic stability c. Post op nausea, vomittingTimepoint: a. Baseline b. 5, 10, 15, 30 min, 45 min, 1 hr, 1hr 30 min, 2 hr after induction c. 1 hr, 2 hr, 4 hr, 6hr, 12 hr, 24 hr post surgery	—

Countries

India

Contacts

Public ContactDr MAJ Sourabh Kumar

Rajendra Institute of Medical Sciences

drvishwanathkumar@gmail.com8439512490

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026