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Restricted fluid therapy in living donor liver transplant

Intraoperative Fluid Therapy-Finding a Balance:A single centre Experience With Restricted Fluid Therapy In Adult Living Donor Liver Transplant - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2025/05/087220
Enrollment
400
Registered
2025-05-20
Start date
Unknown
Completion date
Unknown
Last updated
2025-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K703- Alcoholic cirrhosis of liver Health Condition 2: K77- Liver disorders in diseases classified elsewhere Health Condition 3: K746- Other and unspecified cirrhosis ofliver Health Condition 4: K76- Other diseases of liver

Interventions

Intervention1: Nil: Nil Intervention2: Nil: Nil

Sponsors

Dr Amit Singhal
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All patients over 18years of age undergoing adult living donor liver transplant from December 2021 to November 2023 will be enrolled in the study.

Exclusion criteria

Exclusion criteria: - Patients less than 18years of age. - Patients with H/O recent (less than one week) Hepatorenal syndrome/Acute Kidney Injury - Patients with known H/O chronic kidney disease - Patients with Hepatopulmonary syndrome/Portopulmonary Hypertension - Combined procedure with liver transplant. - H/O hepatic encephalopathy (Grade 2 or more at the time of transplant) - Patients with acute liver failure. INTRAOPERATIVE- - Patients requiring intraoperative continuous renal replacement therapy - Patients with incomplete data POSTOPERATIVE - Patient requiring mechanical ventilation for graft dysfunction or neurological complications. - Patient requiring mechanical ventilation for renal replacement therapy

Design outcomes

Primary

MeasureTime frame
Evaluate our rate of early extubation (on-table extubation, extubated within 4hours postoperatively) after living donor liver transplant, mean duration of mechanical ventilation, pulmonary complications such as pulmonary edema , pleural effusion requiring drainage within 72 hours postoperatively. â?¢Incidence of Acute kidney injury within 72 hours postoperatively. Need for renal replacement therapy. Timepoint: 72 hours—

Secondary

MeasureTime frame
Intraoperative need for packed red blood cells, vasopressor requirement (noradrenaline-mcg/kg/min and total vasopressin units) and rate of vascular complications (hepatic artery thrombosis)Timepoint: Intraoperative period—

Countries

India

Contacts

Public ContactDr Amit Singhal

BLK Max Superspeciality Hospital

drsinghalamit@gmail.com09891873774

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026