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Evaluation of 2% Nanocurcumin Gel With or Without Laser in the Treatment of Gum Disease (Periodontitis)

Effect of 2% nanocurcumin gel with and without photodynamic therapy as an adjunct to open flap debridement in the management of chronic periodontitis patients A clinico-microbial study - NIL

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/05/087186
Enrollment
11
Registered
2025-05-20
Start date
Unknown
Completion date
Unknown
Last updated
2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: open flap debridement with antimicrobial photodynamic therapy: sites will be treated with 2%Nano-curcumin gel with antimicrobial photodynamic therapy (using diode laser 445 5nm) as an

Sponsors

DR Harshavardhan G N
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients within the age range of 30-60 years of either sex. 2. Patients who were systemically healthy. 3. Patients having minimum two sites in different quadrants with periodontal pocket depth (PPD)greater than or equal to 5mm and clinical attachment loss (CAL) greater than or equal to 3mm, associated with horizontal bone loss radiographically.

Exclusion criteria

Exclusion criteria: 1.Patients with the habits like smoking and alcohol consumption. 2. Patients with large carious lesions or any periapical infections. 3. patients with history of antibiotics usage or history of periodontal surgery in last six months. 4. Pregnant and lactating women. 5. Patients who are non-compliant or physically challenged. 6. Patients who are not able to maintain the oral hygiene or not able to follow up for their recall visit.

Design outcomes

Primary

MeasureTime frame
1.Probing pocket depth (PPD) 2. Clinical attachment level (CAL) /relative attachment level using acrylic stent 3. Microbial biomarker: subgingival plaque P. gingivalisTimepoint: 3 months

Secondary

MeasureTime frame
1.Plaque Index (PI) 2. Gingival Bleeding Index (BI)Timepoint: 3 months

Countries

India

Contacts

Public ContactDr GAYATHRI G V

Bapuji dental college and hospital

gayathri_dental@rediffmail.com09886593224

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: May 1, 2026