Health Condition 1: K053- Chronic periodontitis
Conditions
Interventions
Intervention1: Platelet rich fibrin integrated Tranexamic acid: All surgical procedures are performed under local anesthesia (2% lidocaine with
1:80000 epinephrine). Intracrevicular incisions are made
Sponsors
Government Dental College And Research institute Bangalore
Eligibility
Inclusion criteria
Inclusion criteria: Age 18 to 60 years of both gender. Participants with diagnosis of periodontitis Stage III or IV. Full mouth plaque score 15 percent(PI 1.5) & full mouth bleeding score (FMBS 15 percent ) at the time of enrolment. Participants in good general health (ASA I) Etiological periodontal therapy completed at least 3 months prior to the screening. Presence of one natural tooth having a vertical defect with residual probing depth (PD)5 mm and radiographic intrabony component 3mm and radiographic angle of defect between 25 to 45 degree.
Exclusion criteria
Exclusion criteria: Grade C periodontitis. Smoking habits. Pregnancy and lactation. History of periodontal surgery or prosthetic restorations at the experimental teeth. Mobility of teeth greater than Grade II. Non vital teeth or trauma from occlusion. Known Allergy from Tranexamic acid.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Evaluation of changes in the Level of PDGF-BB in the wound fluid of three treatment groups as assessed on Baseline,1st, 7th,14th, 21st and 30th days.Timepoint: Baseline,1st, 7th,14th, 21st and 30th days. | — |
Secondary
| Measure | Time frame |
|---|---|
| Wound Healing as assessed by Wachtel Index on 7th , 14th , 21st and 30th days.Timepoint: 7th , 14th , 21st and 30th days. | — |
Countries
India
Contacts
Public ContactDr Shreya Chandra
Government dental college and research institute
Outcome results
None listed