Comparison of Dexmedetomidine and Remifentanil medications used to keep patients calm and comfortable while they are awake during a placement of breathing tube in difficult patients

Comparasion of dexmedetomidine and remifentanil for sedation during awake fibre-optic intubation in patients with difficult airway- a randomized clinical control trial - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/05/087160

Enrollment

Registered

2025-05-20

Start date

Unknown

Completion date

Unknown

Last updated

2025-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Dexmedetomidine: Dexmedetomidine loading dose of 0.5 g/kg over 10 minutes Intravenously and continuous infusion at 0.3 g/kg/hr Intravenously given till appropriate sedation level reach

Eligibility

Inclusion criteria

Inclusion criteria: American Society of Anesthesiologists grades 1 and 2,Undergoing oral cancer or dental surgeries,Patients with limited mouth opening of less than 2 fingers

Exclusion criteria

Exclusion criteria: Patient not giving consent,known allergy to the anesthetics,Coagulation disorders,Pregnancy or breast feeding,Cardiovascular and neurological abnormalities,Non cooperative patients Patients belonging to ASA more than 2,Patients with alcohol or drug use

Design outcomes

Primary

Measure	Time frame
To assess the ease of intubation between both the groupsTimepoint: 1 minute, 5 minute, 10 minute, 15 minute intervals	—

Secondary

Measure	Time frame
To assess intubation comfort score,To study complications, cardio respiratory status intra operatively,Ramsay Sedation scale,Airway obstruction score,Time for IntubationTimepoint: 1 minute, 5 minute, 10 minute, 15 minute intervals	—

Countries

India

Contacts

Public ContactDr Prasanth Sai Vangapulusu

IMS AND SUM HOSPITAL

drranjitaacharya@gmail.com8763421899

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026